6 Genetic Disorders That Can Cause Infertility In Male

Infertility is a multifactorial issue, which means it can happen for several reasons. Also, it is not confined to a specific gender and impacts both males and females. Amongst the several factors that cause infertility, genetics is a crucial factor. Although not all genetic issues cause infertility, some of them do, which results in infertility. The article entails genetic disorders that can cause male infertility and make it harder for such men to conceive. However, treatment from the best IVF hospital in Punjab can help enhance your chances of conceiving successfully. Thus, it is crucial to consult a specialist before planning to conceive, especially if you have any genetic disorders. 

6 Genetic Disorders That Can Cause Infertility In Male

In males, different factors are responsible for causing infertility or fertility, and genetics is also a common factor. These are some of the genetic disorders that can cause infertility in men:

  • Klinefelter Syndrome (KS): It is a genetic condition that some males are born with. In this condition, the male is born with an extra X chromosome, which can happen due to random genetic error after conception, which is called meiotic nondisjunction of chromosomes. It can cause low testosterone production, facial and body hair, and reduced muscle mass. Such males have little to no sperm production, which can lead to infertility. Its treatments include fertility treatments or testosterone replacement. 
  • Kallmann Syndrome: It causes an impaired sense of smell and delays puberty. It can occur in both men and women but is more common in the former than in the latter. It causes undescended or partially descended testicles, facial defects, such as cleft lip or palate, small penile size, infertility and more. If males with this syndrome wish to have children, they need hormone replacement therapy. Consult the best IVF centre in Punjab to determine which treatment works best for you. 
  • Cystic Fibrosis (CF): It is a disorder caused due to genetic defects. Most men with cystic fibrosis are infertile because of the absence of a sperm canal or vas deferens (CBAVD). As the sperm canal is missing in such people, sperm cannot enter the semen, making it impossible to reach and fertilise the egg, which results in infertility. Although this condition makes males infertile, they are not sterile as they still produce sperm. Despite this condition, men can have biological children through ART (Assisted Reproductive Technology) Techniques. Consult the best doctor from the best IVF centre in Bathinda to know which ART technique will suit you the best. 
  • Y Chromosome Microdeletions: Y chromosomes are present only in males, and microdeletion is another major cause of male infertility. The Y chromosome contains genetic information that determines male characteristics and influences sperm development. Microdeletion means the area of that gene is missing, and Y chromosome microdeletion can impact sperm production. It can cause no sperm production, impaired sperm, low sperm count and immotile sperm. Its treatment is available from the best IVF centre in Punjab. However, the treatment depends on the extent of deletion and other factors. Thus, it is crucial to consult an expert.  
  • Chromosome Rearrangement: It can happen in both males and females. Chromosome rearrangement means chromosomes are missing, deleted or altered. This can cause structural abnormalities, affect sperm production, motility and morphology and reduce fertility. ART techniques can help people with chromosome rearrangement, but the treatment will depend on the type of issue and its severity.  
  • Structural Abnormalities: It is another issue that can happen due to genetic error. Structural abnormalities such as the underdeveloped or irregular shape of reproductive organs can affect fertility in males. Issues such as the absence of vas deferens can also cause infertility. Depending on the abnormality, the doctors can recommend various treatment options and can help you conceive successfully. 

Conclusion

Genetics has a huge role to play in the development of the whole body, and reproductive organs are no exception. Genetics, to some extent, can cause infertility in males. Genetic disorders such as chromosome rearrangement, Y chromosome microdeletion, Kallmann Syndrome, Klinefelter Syndrome, Cystic Fibrosis, and Structural abnormalities can affect fertility and also cause infertility. However, you can get treatment for these genetic disorders from the best IVF centre in Bathinda and improve your chances of successful conception.

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